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N-Acetyl Cysteine Supplements Review & Top Picks
Clinical proxy — fosgonimeton (ATH-1017), Athira's distinct HGF/MET positive modulator from the same lineage: Phase 1 was clean (up to 90 mg subcutaneous, mainly injection-site pain and pruritus, no serious adverse events), but the LIFT-AD Phase 2/3 trial missed its primary and key secondary endpoints in September 2024 in a 312-patient primary analysis population, over a 26-week treatment period (GST change -0.08, p = 0.70)
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Cellular and Molecular Life Sciences 65: 2008
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