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In one single-center trial of 72 subjects using a controlled-adverse-environment model, the Tβ4 eye drop did not meet its co-primary endpoints (ocular discomfort and inferior corneal staining) at the primary time point, but it did produce statistically significant improvements on several secondary endpoints, including central and superior corneal staining, with no adverse events reported

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[DOI] [PubMed] [Google Scholar] 21.Neogi T, Ellison RC, Hunt S, Terkeltaub R, Felson DT, Zhang Y