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Identification of novel glutathione adducts of benzbromarone in human liver microsomes - ScienceDirect
In vitro studies described a cluster transfer between Grx3-Bol2 and Aft2, involving a ligand exchange mechanism and a specific protein–protein interaction that requires Aft2 Cys187 [148,149]
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As shown in Figure 5, left ventricular contractile dysfunction and arterial vascular disease are significant contributors to the development of hypertension, suggesting a potential pathway through which NNMT may influence hypertension
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