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New trial data on CagriSema — 23% weight loss at 84 weeks in the RE-DEFINE 4 trial. CagriSema pairs semaglutide with cagrilintide, an amylin analogue. Amylin is a pancreatic hormone that slows

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One fraction for analysis of GSH-derived metabolites was immediately precipitated with MeOH and after evaporation, obtained residue was resuspended in 50 μL of 50 mM HEPES (pH 7.4), diluted with 20% ACN (containing 0.1% FA and mixture of internal standards) and immediately analysed by LC-MS/MS