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In vitro / cell culture Fibroblast migration, F-actin, FAK–paxillin, growth hormone receptor expressionExtensive Animal models — chiefly rat Transected Achilles tendon, gastrointestinal injury, vascular and neurological modelsExtensive Human clinical data Three pilot studies in total, per a 2025 review of the musculoskeletal literatureMinimal Large randomised controlled trials in humans None FDA approval Not approved for use in standard medicine by FDA or other regulatorsNone WADA status 2026 Prohibited List, S0 — named explicitly

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There are conflicting recommendations [48] [50] regarding whether to change the dosing of oral acetylcysteine after the administration of activated carbon, and even whether the dosing of acetylcysteine needs to be altered at all