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In contrast, the Wnt/β-catenin activator LiCl reversed all anti-tumor phenotypes induced by AHNAK2 gene silencing [118], indicating that inhibition of this pathway can delay TC progression
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This defined stoichiometry means each molecule delivers exactly one copper ion, allowing researchers to calculate precise copper concentrations in their experimental systems — a critical consideration since copper is biologically active at nanomolar concentrations but cytotoxic at micromolar levels
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