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The Neh1 domain is located at the C-terminus of the NRF2 protein and contains the CNC and bZIP regions, which can bind to specific sequences on DNA to regulate the transcription of downstream genes
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Renal Renal injury was evaluated by assessing glomerular vacuolization (GV), tubular dilation (TD), vascular vacuolization and hypertrophy (VVH), tubular cell degeneration and necrosis (TCDN), Bowman space dilation (BSD), tubular hyaline cylinders (THC), lymphocyte infiltration (LI), and tubular cell shedding (TCS) [48]
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