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LITERATURE CITED 1.World Health Organ

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Size:15 Tablets

Binding of Cu(II) ions to ceruloplasmin Our results confirm that at pH 7.4 Cu•CP complex can not be demetallated with high millimolar concentrations of strong Cu(II)-chelating ligands like EDTA or DTPA in a timeframe of up to 20 h, which could be explained with three possibilities: first – the thermodynamic Cu(II)-binding affinity of Cu•CP is much higher as compared to chelators used (for EDTA K D = 1.26 × 10 −16 M 30