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Accumulating evidence indicates that increased level of pro-inflammatory chemokines: CCL2, CCL4, CCL11, CCL17, CCL22, and CCL24, in serum strongly correlates with schizophrenic symptoms including cognitive impairments in attention, working memory, episodic and semantic memory, and executive functions [11,261,262,263,264,265,266,267,268]
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The binding of cadmium or arsenic to SOD diminishes its enzymatic activity, whereas curcumin forms hydrogen bonds with histidine residues, thereby reducing SOD’s affinity for arsenic and cadmium and restoring its activity (Wahyudi et al., 2022)
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