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Peptide-based treatments may be worth discussing in selected cases: Patients with early thinning who already understand that medical therapy remains the foundation Patients using minoxidil or DHT-directed therapy who want additional scalp support Patients after hair transplantation where scalp healing and graft environment matter Patients who cannot tolerate certain treatments and need a conservative supportive plan Patients interested in regenerative add-ons who accept the limits of current evidence They are less appropriate for patients expecting dramatic regrowth, patients with advanced bald areas, or patients looking for a “natural” replacement for proven medication
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One small study found 37.5% of treated patients reported lighter skin versus 18.7% on placebo, but effects faded within about six months and side effects occurred in nearly one-third of participants
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