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Clinical signs of riboflavin deficiency include sore throat, redness and swelling of the lining of the mouth and throat, cracks or sores on the outsides of the lips (cheliosis) and at the corners of the mouth (angular stomatitis), inflammation and redness of the tongue (magenta tongue), and a moist, scaly skin inflammation (seborrheic dermatitis)

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Studies focused on peripheral pain generator blockade suggest that fibromyalgia symptoms should either disappear or not develop with such a blockade [12,46]