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To prevent this, use the smallest gauge needle practical for drawing doses (29-31 gauge insulin needles), always insert the needle straight (not at an angle), and try to puncture the same spot on the stopper each time rather than creating new holes across the surface
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doi: 10.3390/antiox10071087, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 125.Nopriyati NR, Thaha A, Diba S, Yahya YF, Aryani IA
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