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Both of these transport mechanisms were increased in the alveolar epithelium of ethanol-fed animals, likely as a compensatory response to any fluid imbalances.22,24 Additionally, the lungs of ethanol-exposed animals had decreased net vectorial fluid transport (i.e., reduced movement of specific solutes or water from one compartment to another) in vivo compared with animals fed a control diet, despite the compensatory increase in epithelial sodium channel and Na/K-ATPase function