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Potential therapeutic interventions targeting mitochondrial dynamics, bioenergetic support, and inflammation modulation are explored, highlighting emerging strategies such as mitochondrial-targeted antioxidants, metabolic substrate supplementation, and pharmacological regulators of mitochondrial permeability transition pores
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In patients with longer disease duration, the abundance of Fournierella and DTU089 (Ruminococcaceae) increased, while that of Roseburia (Lachnospiraceae) decreased
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