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As a pharmacologic therapeutic, optimizing the efficacy of GSH and minimizing its unintended effects means it is crucial to determine the correct timing, dose, and disease context (Hong et al., 2005)

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After the pull down of lysates made in GSH-depleted cells no capsid proteins were detected from the 5S, 14S and 75S peaks and only trace amounts of capsid proteins were visible in the 150S peak (Figure 7E, lanes 7–10)