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This could also prove beneficial by decreasing replication in those tissues with lower oxygen tension, such as the brain and some mucous membranes (oral and digestive), where conditions of relative hypoxia allow certain viruses, such as EBV, to enter the lytic phase and replicate and thus generate reservoirs and greater inflammation in these tissues [414–416]
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Co-Delivery of doxorubicin and aptamer against Forkhead box M1 using chitosan-gold nanoparticles coated with nucleolin aptamer for synergistic treatment of cancer cells
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