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SETMAR, a histone methyltransferase containing an N-terminal histone-lysine N-methyltransferase catalytic domain and a C-terminal transposase domain, possesses catalytic activity for methylation at histone H3K4me2, H3K36me2, and H3K27me3 sites, thereby regulating gene transcription [65, 66]
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Pharmacodynamics is a division of biochemical pharmacology that defines the relationship between plasma and tissue drug and metabolite concentrations, time, and biological response
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