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The same experiment in the neuron-like FXN-deficient SKAN cells demonstrated a lack of NQO1 or Grx response after t BHQ treatment or NQO1, Grx, and GST-P1 increase after oligomycin treatment
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Nrf2 is well known for mediating the expression of antioxidant and detoxifying proteins in response to oxidative and electrophilic stress (reviewed in [162, 163])
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