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As can be seen on the flow cytometry histograms of AO staining (Fig 8D–8F), dysregulation of the AVO compartment was minimal when cells were treated with As 2 O 3 (with a mean red fluorescence of 329 ± 89 compared to the control of 249 ± 69) (Fig 8D and 8E), whereas NaAsO 2 treatment induced a slight decrease of AVOs and promoted a clear apoptotic/necrotic cell death as observed in the same conditions for the P3HR1 + cells (Fig 6)

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[DOI] [PubMed] [Google Scholar] 9.Huang D.Q., Singal A.G., Kono Y., Tan D.J.H., El-Serag H.B., Loomba R