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Silencing of Glucocerebrosidase gene in Drosophila enhances the aggregation of Parkinson's disease associated α-Synuclein mutant A53T and affects locomotor activity

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We expect that physicians typically do not have the case volume to justify an investment in the infrastructure needed to adequately provide the care coordination services required under TEAM (such as dedicated support staff for case management), which leads us to believe that as a result, the physician, PGP, and model would have more challenges if physicians and PGPs were TEAM participants