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The clinician must determine whether any proposed treatment is appropriate after reviewing risks, alternatives, and your health history
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In vitro radioligand binding studies revealed that kratom alkaloids interact with opioid μ, δ, κ subtypes, and non-opioid receptors including alpha-1A, alpha-2A, 5-HT1A, 5-HT2A, D1, and D2 (Takayama et al., 2002
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