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I sometimes randomly get a metallically taste in the back of my throat, very rare but when I notice I have to drink water and it's almost like when your sick and

Interestingly, ursodeoxycholic acid, the only treatment approved by the Food and Drug Administration for the treatment of primary biliary cirrhosis, a chronic cholestatic disorder, was shown to prevent the fall in GCL expression during chronic cholestasis (Serviddio et al., 2004) and increase GCL expression in cultured rat hepatocytes (Mitsuyoshi et al., 1999)

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Most patients begin noticing weight loss within the first month, with continued improvement over time