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Mechanistically, mavacamten promotes the folding of myosin heads back onto the filament backbone into the SRX state, while aficamten stabilizes myosin in a weak-actin binding conformational state
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Models Mimicking Sinusoids As explained in Section , the liver sinusoid, constituting the liver’s basic repeating microscopic unit, contains various types of hepatic cells organized in a controlled environment to maintain hepatic functions
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