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Oxidative Stress and Systemic Inflammation: Far beyond the Articular Damage Chronic inflammation, a prominent feature of RA, contributes to the increment in cardiovascular risk in its carriers [33, 34], as the risk factors classically described for cardiovascular morbimortality, namely, smoking, hypertension, diabetes mellitus, obesity, and sedentary lifestyle, do not completely explain the increased cardiovascular risk observed in RA patients [29]
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