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Researchers studying mitochondrial biogenesis pathways use SLU-PP-332’s ERR-agonist mechanism alongside 5-Amino-1MQ’s NNMT-inhibition mechanism to probe whether combined pathway engagement produces distinct signaling profiles compared to either compound studied alone
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Mutagenesis The following battery of mutagenicity assays revealed no potential for mutagenesis: bacterial mutation (Ames), alkaline elution, rat micronucleus, sister chromatid exchange, CHO/HGPRT mammalian cell forward gene mutation, and unscheduled DNA synthesis (UDS)
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