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In a parallel randomised, double-blind clinical trial study (Namkhah et al., 2021), NIN capsules (100 mg) consumption significantly reduced percentages of NAFLD grades, as well as, serum levels of triglyceride, total cholesterol, and low-density lipoprotein and increased serum level of high-density lipoprotein compared with the control group in overweight/obese patients with NAFLD
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A higher accumulation of polyamines like putrescine was also observed, contributing to cellular protection
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