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In this section, we review different classes of treatment agents undergoing clinical trials (Table 2), including vitamins [229, 230], FGF21 agonist antibodies or analogs [231, 232], diets [233], combined metabolic activators (CMAs) [234], anti-T2DM drugs [235], PPARγ agonist [236], regulation of lipogenesis [237], bacterial alteration [238], hormone therapy [239], and C-C chemokine receptors antagonist [240]
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Moreover, the formation of protein complexes associated with TNFR1 through RIPK1 has been observed in screenings of necrotic and apoptotic regulators
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