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showed that the administration of agmatine in BDL rats for seven days after bile duct ligation was able to reduce ROS and nitric oxide formation and lipid peroxidation, and to increase mitochondrial GSH both in the liver and in the kidney in a dose-dependent way [200]
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To confirm the predicted interaction between MTRR ∆FMN and MTR, we expressed and purified a GST-tagged construct of MTRR ΔFMN (Fig
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