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The effects of ANP on lipolysis are more relevant to primates than rodents, as rodents express over 100 times the level of the clearance receptor NP clearance receptor (NPCR), which mitigates the effect of ANP on lipolysis (112, 113)
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Of these, 9% of patients had Grade III or IV chondral lesions and were under 50 years old, meeting conservative indications for cartilage repair surgery
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