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Moreover, carvedilol was also shown to improve skeletal muscle contractility, an effect that was also mediated by a β -Arr-dependent pathway, suggesting a potential clinical role of carvedilol in treating diseases associated with muscle wasting such as sarcopenia and secondary muscle wasting (Kim et al., 2020)

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Inhibitory effect of (2R)-4-(4-hydroxyphenyl)-2-butanol 2-O-β-d-apiofuranosyl-(1→6)-β-d-glucopyranoside on RANKL-induced osteoclast differentiation and ROS generation in macrophages